pentobarbital will reduce the extent or result of cariprazine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Contraindicated (1)pentobarbital will decrease the extent or effect of roflumilast by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the extent or influence of colchicine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital decreases levels of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral form of both agents. Insignificant/Importance Unknown.
The use of barbiturates as sedatives within the postoperative surgical time period and as adjuncts to cancer chemotherapy is very well founded
pentobarbital will decrease the level or result of avanafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. For individuals with ED, monitor response very carefully due to possible for lowered usefulness.
Phenytoin and barbiturate blood degrees need to be monitored more routinely if supplied concurrently; outcome of barbiturates on phenytoin metabolism documented to generally be variable; sodium valproate and valproic read more acid seem to reduce barbiturate metabolism; check barbiturate blood amounts and make proper dosage changes as required
pentobarbital will lower the level or effect of amlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lessen the extent or influence of hydrocortisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Continually monitor very important signals during sedation and Restoration interval if coadministered. Thoroughly titrate remimazolam dose if administered with opioid analgesics and/or sedative/hypnotics.
With therapeutic doses of TCAs, barbiturates increase metabolism and reduce blood concentrations of TCAs.
Watch Intently (3)pentobarbital will minimize the extent or outcome of diazepam intranasal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Sturdy or average CYP3A4 inducers may boost fee of diazepam elimination; for that reason, efficacy of diazepam may very well be lowered.
pentobarbital will lessen the level or impact of meloxicam by influencing hepatic enzyme CYP2C9/ten metabolism. Small/Significance Unidentified.
pentobarbital will reduce the level or result of sulfamethoxazole by influencing hepatic enzyme CYP2C9/ten metabolism. Minor/Significance Not known.